Open Clinical Trials
Englewood Hospital’s physician-investigators are currently recruiting research subjects for participation in several clinical trials across various departments.
Cardiology
ACURATE IDE: Transcatheter Replacement of Stenotic Aortic Valve through Implantation of ACURATE in Subjects InDicatEd for TAVR
Principal Investigator: Joseph De Gregorio, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 03735667
Englewood Health IRB #: E-21-860
More Information (clinicaltrials.gov)
Champion AF: WATCHMAN FLX versus NOAC for Embolic Protection in the Management of Patients with Non-Valvular Atrial Fibrillation
Principal Investigator: Grant Simons, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 04394546
Englewood Health IRB #: E-20-839
More Information (clinicaltrials.gov)
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women (ROMA:Women)
Principal Investigator: Molly Schultheis, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 04124120
Englewood Health IRB #: E-23-928
More Information (clinicaltrials.gov)
Evolut™ EXPAND TAVR II Pivotal Trial
Principal Investigator: Ramin Hastings, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 05149755
Englewood Health IRB #: E-23-948
More Information (clinicaltrials.gov)
Gastroenterology / C Diff
Fecal Microbiota Transplantation (FMT) for the Treatment of Recurrent or Refractory Clostridium Difficile Infection (CDI)
Principal Investigator: Marc Fiorillo, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 01942447
Englewood Health IRB #: E-13-507
More Information (clinicaltrials.gov)
Gynecology
A randomized controlled trial to evaluate the efficacy of acupuncture versus aromatherapy as treatments to lessen nausea and vomiting associated with Adriamycin and Cytoxan
Principal Investigator: Tracy Scheller, MD
Coordinator: Nathalia Clark
Phone: 201-894-3088
NCT #: 04116697
Englewood Health IRB #: E-19-773
More Information (clinicaltrials.gov)
Neurological Surgery
A Multicenter Observational Study of GammaTile™ Surgically Targeted Radiation Therapy (STaRT) in Intracranial Brain Neoplasms
Principal Investigator: Kevin Yao, MD
Coordinator: Nathalia Clark
Phone: 201-894-3088
NCT #: 04427384
Englewood Health IRB #: E-21-856
More Information (clinicaltrials.gov)
A Prospective, Concurrently Controlled, Multi-Center Study to Evaluate the Safety and Effectiveness of the Spinal Kinetics M6-C™ Artificial Cervical Disc Compared to Anterior Cervical Discectomy and Fusion (ACDF) for the Treatment of Contiguous Two-Level Symptomatic Cervical Radiculopathy
Principal Investigator: Yakov Gologorsky, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 04982835
Englewood Health IRB #: E-22-906
More Information (clinicaltrials.gov)
Oncology
A021806: A Phase III Trial of Periperative vs. Adjuvant chemotherapy for Resectable Pancreatic Cancer
Principal Investigator: Minaxi Jhawer, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 04340141
Englewood Health IRB #: E-21-848
More Information (clinicaltrials.gov)
A Multicenter, Double-blind, Randomized Phase 3 Study to Compare the Efficacy and Safety of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab, in the Adjuvant Treatment of Clear Cell Renal Cell Carcinoma (ccRCC) Post Nephrectomy (MK-6482-022)
Principal Investigator: Brian Kim, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 05239728
Englewood Health IRB #: E-22-880
More Information (clinicaltrials.gov)
A Phase IB/II Multi-Cohort Study of Targeted Agents with Atezolizumab for Patients with Recurrent or Persistent Endometrial Cancer [EndoMAP]
Principal Investigator: Nimesh Nagarsheth, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 04486352
Englewood Health IRB #: E-21-868
More Information (clinicaltrials.gov)
A Phase II/III randomized study of R-miniCHOP with or without CC-486 (oral azacitidine) in patients age 75 years or older with newly diagnosed diffuse large B cell lymphoma, Grade IIIb Follicular Lymphoma, transformed lymphoma, and high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements [S1918]
Principal Investigator: Adam Zayac, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 04799275
Englewood Health IRB #: E-21-873
More Information (clinicaltrials.gov)
Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients With Advanced Stage Cancer
Principal Investigator: Vinnidhy Dave, DO
Coordinator: Nathalia Clark
Phone: 201-894-3088
NCT #: 05170919
Englewood Health IRB #: E-21-862
More Information (clinicaltrials.gov)
Oncology / Bladder Cancer
A phase II study of dose-dense gemcitabine plus cisplatin (ddGC) in patients with muscle-invasive bladder cancer with bladder preservation for those patients whose tumors harbor deleterios DNA damage response (DDR) gene alterations
Principal Investigator: Brian Kim, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 03609216
Englewood Health IRB #: E-18-748
More Information (clinicaltrials.gov)
Oncology / Breast Cancer
A011801: The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD), A Double-Blinded, Phase III Randomized Trial of T-DM1 and Placebo Compared with T-DM1 and Tucatinib
Principal Investigator: Jill Morrison, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 04457596
Englewood Health IRB #: E-21-850
More Information (clinicaltrials.gov)
MarginProbe 2.0 Data Collection Protocol
Principal Investigator: Jenna Gillen, DO
Coordinator: William Dippolito
Phone: 201-608-2572
NCT #: 05377229
Englewood Health IRB #: E-24-960
More Information (clinicaltrials.gov)
Oncology / Colon Cancer
A021703: Randomized Double-Blind Phase III Trial of Vitamin D3 Supplementation in Patients with Previously Untreated Metastatic Colorectal Cancer (SOLARIS)
Principal Investigator: Minaxi Jhawer, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 04094688
Englewood Health IRB #: E-19-792
More Information (clinicaltrials.gov)
Oncology / Gastric Cancer
IMIGASTRIC II: Prospective, observational, multicenter study on minimally invasive gastrectomy for gastric cancer: robotic, laparoscopic and open surgery compared on operative and follow-up outcomes
Principal Investigator: Steven Brower, MD
Coordinator: Nathalia Clark
Phone: 201-894-3088
NCT #: 02751086
Englewood Health IRB #: E-16-673
More Information (clinicaltrials.gov)
Oncology / Gynecology
A Phase II, Single-Arm Study of Giredestrant in Participants With Grade 1 Endometrial Cancer
Principal Investigator: Nimesh Nagarsheth, MD
Coordinator: Audrey Ades
Phone: 201-894-3603
NCT #: 05634499
Englewood Health IRB #: E-22-913
More Information (clinicaltrials.gov)
Vascular Surgery
A Post-Market, Multi-Center, Prospective, Interventional Study using the Venclose™ System and Venclose MAVEN™ System for Treatment of Chronic Venous Insufficiency of the Great and Small Saphenous Veins and Incompetent Perforator Veins
Principal Investigator: Steven Elias, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 05504070
Englewood Health IRB #: E-22-910
More Information (clinicaltrials.gov)
Evaluation of the GORE® VIAFORT Vascular Stent for Treatment of Symptomatic Iliofemoral Venous Obstruction
Principal Investigator: Steven Elias, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 05489588
Englewood Health IRB #: E-22-912
More Information (clinicaltrials.gov)
Extracorporeal Flow Abolition in Relation with Primary Insufficiency of Great Saphenous Veins (GSV) using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study (VEINRESET)
Principal Investigator: Steven Elias, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 05926830
Englewood Health IRB #: E-23-936
More Information (clinicaltrials.gov)
VERITAS (S2473) – A Phase 4 Randomized Trial Comparing Varithena to Endothermal Ablation for the Treatment of the Great Saphenous Vein
Principal Investigator: Steven Elias, MD
Coordinator: Joseph Valeri
Phone: 201-894-4283
NCT #: 05312970
Englewood Health IRB #: E-22-895
More Information (clinicaltrials.gov)